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Breakthrough Discovery in Triple Negative Breast Cancer

The Canadian Breast Cancer Foundation - BC/Yukon Region is excited to share with you the news of a significant breakthrough in breast cancer research, funded in part by CBCF and our supporters. The study, published online last month in the international journal Nature, reports on the research that has decoded the genetic make-up of triple negative breast cancer. The Foundation applauds the research, led by Dr. Samuel Aparicio of the BC Cancer Agency, and Dr. Marco Marra, director of the Michael Smith Genome Sciences Centre at the BC Cancer Agency. Also on the team was CBCF-funded fellow, Dr. Sohrab Shah.

Triple negative breast cancer is currently treated as if its a single disease, yet its clear from this study that patientstumours vary drastically in the cancers development. Currently, triple negative breast cancer accounts for 16 per cent of all breast cancer diagnoses and approximately 25 per cent of breast cancer deaths. The research results will lead to more effective treatment of the disease.

Whats extremely motivating with these findings is the opportunity to design clinical trials for patients with triple negative breast cancer so we can explore patient responses to treatment at the genetic level and look at ways to improve therapies and outcomes for patients, says Dr. Sam Aparicio, Nan and Lorraine Robertson Chair of Breast Cancer Research, UBC/BC Cancer Agency; and Canada Research Chair in Molecular Oncology.

The research was funded by the BC Cancer Foundation and the BC Cancer Agency, the Canadian Breast Cancer Foundation (BC/Yukon and Prairies/NWT Regions), with additional support from The Canadian Institutes for Health Research (CIHR), Genome Canada, Genome BC, The Canada Foundation for Innovation and the Michael Smith Foundation for Health Research (MSFHR).


Pictured, from left to right: Dr. Marco Marra, Wendy Slavin, CBCF BC/Yukon, Dr. Sam Aparicio, Tracy Sopkow, CBCF Prairies/NWT and Dr. Sohrab Shah

This discovery was made possible in part by you, our donors and supporters of the Canadian Breast Cancer Foundation. Thank you to each and every one of you who made this important discovery happen. Because of you, we are indeed one step closer to a future without breast cancer.

To read the full press release, please click here, or to learn more about our granting process visit our website at www.cbcf.org.